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RET p.M918T Reference Standard

CBP10483

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description RET M918T lies within the protein kinase domain of the Ret protein (Uniprot.org). M918T results in ligand-independent autophosphorylation of Ret and increased substrate binding, is transforming (PMID: 17108110), and confers drug resistance in the context of KIF5B-RET in culture (PMID: 29908090).
   
Technical Data 
DNA Change: c.2753T>C
AA Change p.M918T
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 75%
Transcript ENST00000355710.7
Cosmic ID COSM965
Chr position(GRCh37) chr10:43617416
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

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