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PTPN11 p.G60R Reference Standard

CBP10537

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Introduction 
Format Genomic DNA
Description PTPN11 G60R lies within the SH2 domain 1 of the Ptpn11 protein (UniProt.org). G60R has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Ptpn11 (PMID: 29533785), and therefore, is predicted to have no effect on Ptpn11 protein function.
   
Technical Data 
DNA Change c.178G>C
AA Change p.G60R
Mutation type Missense_Mutation
Zygosity Heterozygous
Allelic Frequency 50%
Transcript NM_002834.5
Cosmic ID COSM13010
Chr position(GRCh37) chr12:112888162
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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