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NPM1 p.N38D Reference Standard

CBP10545

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description NPM1, nucleophosmin, is a phosphoprotein that shuttles between the nucleus and cytoplasm, and is involved in several cellular processes including ribosomal processing and export, chromatin remodeling, DNA replication and repair, and cell cycle control (PMID: 29157973, PMID: 23436734). NPM1 is frequently mutated in acute myeloid leukemia (PMID: 29157973, PMID: 23436734, PMID: 30122998, PMID: 29785446, PMID: 32203582, PMID: 32609823) and overexpression is implicated with poor prognosis in hematological and solid tumors (PMID: 32071709).
   
Technical Data 
DNA Change c.112A>G
AA Change p.N38D
Mutation type Missense_Mutation
Zygosity Heterozygous
Allelic Frequency 50%
Transcript NM_002520.7
Cosmic ID N/A
Chr position(GRCh37) chr5:170817108
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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