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MDM2 T309G (rs2279744-T/G) Reference Standard

CBP10630

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Introduction 
Format Genomic DNA
Description MDM2, MDM2 proto-oncogene, is an E3 ubiquitin protein ligase that mediates Tp53 degradation and therefore, regulates apoptosis and cell-cycle. Amplification and/or overexpression of MDM2 has been identified in several cancer types and amplification is common in liposarcoma and has been observed with Mdm2 overexpression in anaplastic lymphoma kinase (ALK)-negative inflammatory myofibroblastic tumors.
   
Technical Data 
DNA Change: c.-5+309T>G
AA Change T309G (rs2279744-T/G) 
Mutation type N/A
Zygosity Heterozygous
Allelic Frequency 50%
Transcript ENST00000258149.5
Cosmic ID N/A
Chr position(GRCh37) chr12-69202580-T-G
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

 

 

 

 

 

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