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FGFR2 p.N550K Reference Standard

CBP10475

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Introduction 
Format Genomic DNA
Description FGFR2 N550K (corresponds to N549K in the canonical isoform) lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). N550K results in increased Fgfr2 kinase activity and enhanced cell proliferation in the presence of ligand in culture (PMID: 23908597).
   
Technical Data 
DNA Change: c.1650T>G
AA Change p.N550K
Mutation type Substitution - Missense
Zygosity Homozygous
Copy Number 3
Ploidy 2.17
Allelic Frequency 100.00%
Transcript ENST00000457416.6
Cosmic ID COSM36902
Chr position(GRCh37) chr10:123258034
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

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