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CHEK1 p.L355* Reference Standard

CBP10540

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索取COA
产品描述
产品数据库
Introduction
Format Genomic DNA
Description CHEK1, checkpoint kinase 1, is a serine/threonine kinase activated in response to DNA damage that is responsible for mediating checkpoint signaling from ATM and ATR (PMID: 23613359, PMID: 12781359). Overexpression of Chek1 has been observed in several tumor types, including gastric cancer, small cell lung cancer, T-cell leukemia (PMID: 25132270, PMID: 26867682, PMID: 28490518), and breast cancer (PMID: 31933717).
   
Technical Data 
DNA Change: c.1064delT
AA Change p.L355*
Mutation type Frame_Shift_Del
Zygosity Heterozygous
Allelic Frequency 50%
Transcript NM_001274.5
Cosmic ID N/A
Chr position(GRCh37) chr11:125514126
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

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