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AI-Edigene® FLT3 p.I836del Reference Standard Plus

CBP10525

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description
FLT3 I836del results in the deletion of an amino acid in the protein kinase domain activation loop of the Flt3 protein at amino acid 836 (PMID: 12663439). I836del results in constitutive phosphorylation of Flt3 and activation of Stat5, Erk signaling, leading to transformation of cultured cells (PMID: 15256420).
   
Technical Data 
DNA Change c.2508_2510delCAT
AA Change p.I836del
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_004119.3
Cosmic ID COSM797
Chr position(GRCh37) chr13:28592637_28592639
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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