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AI-Edigene® BTK p.C481S Reference Standard Plus

CBP10549

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Introduction 
Format Genomic DNA
Description BTK, Bruton tyrosine kinase, is a non-receptor tyrosine kinase involved in B-cell activation and development (PMID: 24658273). BTK is commonly overexpressed in various hematological malignancies (PMID: 24658273) and BTK mutations have been linked to BTK inhibitor drug resistance (PMID: 28235842).
   
Technical Data 
DNA Change c.1442G>C
AA Change p.C481S
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50.00%
Transcript NM_000061.3
Cosmic ID COSM6053938
Chr position(GRCh37) chrX:100611164
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

 

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